Search results for "genetics [Cerebellar Neoplasms]"

showing 10 items of 3028 documents

Even violins can cry: specifically vocal emotional behaviours also drive the perception of emotions in non-vocal music.

2021

A wealth of theoretical and empirical arguments have suggested that music triggers emotional responses by resembling the inflections of expressive vocalizations, but have done so using low-level acoustic parameters (pitch, loudness, speed) that, in fact, may not be processed by the listener in reference to human voice. Here, we take the opportunity of the recent availability of computational models that allow the simulation of three specifically vocal emotional behaviours: smiling, vocal tremor and vocal roughness. When applied to musical material, we find that these three acoustic manipulations trigger emotional perceptions that are remarkably similar to those observed on speech and scream…

media_common.quotation_subjectEmotionsSingingMusical050105 experimental psychologyGeneral Biochemistry Genetics and Molecular BiologyLoudnessViolin03 medical and health sciences0302 clinical medicinePerceptionHumans0501 psychology and cognitive sciencesmusicHuman voiceResearch Articlesmedia_commonVocal music05 social sciencesVocal tremorArticlesAuditory PerceptionVoiceSingingGeneral Agricultural and Biological SciencesPsychology030217 neurology & neurosurgeryCognitive psychologyPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
researchProduct

The relationship between vigilance capacity and physical exercise: a mixed-effects multistudy analysis

2019

We thank to all the participants who took part in the experiment.

media_common.quotation_subjectPhysical fitnesslcsh:MedicinePoison controlPhysical exerciseFootballGeneral Biochemistry Genetics and Molecular BiologyCognitive demandsbepress|Life Sciences|Neuroscience and Neurobiology03 medical and health sciences0302 clinical medicineCognitionAgeVO2Sport contextbepress|Life Sciences|Neuroscience and Neurobiology|Cognitive NeuroscienceCardiovascular fitnessGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)Cardiovascular fitnessExercisemedia_commonSport typePsychomotor learningPublic healthbusiness.industryGeneral Neurosciencelcsh:RComputingMethodologies_MISCELLANEOUSPsychomotorPsychomotor vigilance task030229 sport sciencesGeneral MedicineKinesiologySustained attentionPsyArXiv|Neuroscience|Cognitive NeurosciencePsyArXiv|Neurosciencebepress|Life Sciences|Neuroscience and Neurobiology|Behavioral NeurobiologyPublic HealthPsyArXiv|Neuroscience|Behavioral NeuroscienceGeneral Agricultural and Biological SciencesPsychologybusinesshuman activities030217 neurology & neurosurgeryClinical psychologyVigilance (psychology)NeurosciencePeerJ
researchProduct

Importance of considering interoceptive abilities in alexithymia assessment

2019

Background Recent studies have shown that people with high alexithymia scores have decreased interoceptive abilities, which can be associated with psychological and physical disorders. Early assessments of the alexithymia trait included the evaluation of these abilities through the dimension measuring the difficulty in identifying and distinguishing between feelings and bodily sensations (the 26-item Toronto Alexithymia Scale; TAS-26). The revised version of the TAS, the TAS-20, contains a three-factor solution that does not involve a dimension assessing interoceptive abilities. However, the three items allowing the evaluation of these abilities are still present in the TAS-20. In this con…

media_common.quotation_subjectlcsh:MedicineContext (language use)Psychiatry and PsychologyGlobal Health050105 experimental psychologyGeneral Biochemistry Genetics and Molecular Biologyfactorial analysisExternal validity03 medical and health sciencesToronto Alexithymia Scale0302 clinical medicineAlexithymiamedicinePersonality0501 psychology and cognitive sciencesComputingMilieux_MISCELLANEOUSmedia_commonmedicine.diagnostic_testGeneral Neuroscience05 social scienceslcsh:Rinteroceptive abilitiesGeneral Medicinemedicine.diseaseExploratory factor analysis[SCCO.PSYC]Cognitive science/PsychologyTraitToronto Alexithymia ScaleAnxietyPublic Healthmedicine.symptomalexithymiaGeneral Agricultural and Biological SciencesPsychology030217 neurology & neurosurgeryClinical psychology
researchProduct

Anger: Adrenaline receptors do not allow us to be too sinful

2013

All of us feel angry once in a while, but if anger turns into a chronic state of mind it is not only annoying to those around us, it may also make us ill. Much of the acute anger reaction is mediated by catecholamines acting on β-adrenoceptors. Chronic activation of these receptors leads to their desensitization, protecting us at least partly from the adverse effects of sustained anger.

media_common.quotation_subjectmental disordersbehavior and behavior mechanismsAngerReceptorPsychologybehavioral disciplines and activitiesNeurosciencepsychological phenomena and processesGeneral Biochemistry Genetics and Molecular Biologymedia_commonThe Biochemist
researchProduct

Medical Records: A Historical Narrative

2022

The history of medical records is thousand-year-long, with earlier roots in ancient civilizations. Until the 19th century, medical records mainly served educational purposes, later assuming other roles such as in insurance or legal procedures. This article comprehensively describes and reviews the development of medical records from ancient to modern times in Europe and North America, reflecting alterations and adaptations compliant with the mental and technological capabilities of a given period. We searched PubMed and Google Scholar databases to collect pertinent articles. English articles or those having English abstracts were considered. The search terms included “Medical Records,” “Hea…

medical recordshistory of medicineMedicine (miscellaneous)eHealthhealthcare systempatient managementGeneral Biochemistry Genetics and Molecular BiologyBiomedicines
researchProduct

Anti-phospholipase A2 and anti-inflammatory activity of Santolina chamaecyparissus

2000

The activity of the Santolina chamaecyparissus methanol extract was tested against the phospholipase A2 (PLA2)-induced mouse paw edema and in vitro inhibition of PLA2 activity. After fractionation, only the dichloromethane extract was active against the PLA2 in vitro test. In addition, it reduced the edema induced by arachidonic acid, and by 12-O-tetradecanoylphorbol-13-acetate in a multidose test. After chromatography on silicagel and gel filtration on Sephadex, and using an in vitro anti-PLA2 assay-guided process, we have isolated and identified from the dichloromethane extract the flavone nepetin and four sesquiterpenes.

medicine.drug_classAsteraceaePharmacologyFlavonesPhospholipases AGeneral Biochemistry Genetics and Molecular BiologyAnti-inflammatorySantolina chamaecyparissusMicechemistry.chemical_compoundPhospholipase A2medicineAnimalsEnzyme InhibitorsGeneral Pharmacology Toxicology and PharmaceuticsFlavonoidschemistry.chemical_classificationPlants MedicinalbiologyPlant ExtractsChemistryAnti-Inflammatory Agents Non-SteroidalGeneral Medicinebiology.organism_classificationIn vitroPhospholipases A2BiochemistrySephadexbiology.proteinFemalelipids (amino acids peptides and proteins)Arachidonic acidSesquiterpenesNepetinLife Sciences
researchProduct

Anti-inflammatory activity in mice of extracts from Mediterranean marine invertebrates.

1998

The effects of dichloromethane and methanol extracts from the marine invertebrates Leptogorgia ceratophyta, Holothuria tubulosa, Coscinasterias tenuispina and Phallusia fumigata on carrageenan-induced paw oedema in mice were investigated. The dichloromethane extract of Coscinasterias tenuispina and the methanol extract of Holothuria tubulosa administered p.o. at 50, 100 and 150 mg/kg, inhibited oedema in a dose-dependent manner 3 h after administration of carrageenan. Both extracts partially decreased elastase activity and PGE2 levels measured in homogenates from inflamed paws, without affecting the levels of this prostanoid present in stomach homogenates. As observed with the selective inh…

medicine.drug_classIndomethacinMarine BiologyPharmacologyBiologyCarrageenanGeneral Biochemistry Genetics and Molecular BiologyAnti-inflammatoryDinoprostonechemistry.chemical_compoundMicemedicineAnimalsEdemaGeneral Pharmacology Toxicology and Pharmaceuticschemistry.chemical_classificationPancreatic ElastaseElastaseHolothuria tubulosaAnti-Inflammatory Agents Non-SteroidalGeneral MedicineMarine invertebratesbiology.organism_classificationInvertebratesCarrageenanEnzymechemistryBiochemistryCoscinasterias tenuispinaFemaleCyclo-oxygenaseLife sciences
researchProduct

Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions

1988

Abstract Most epithelial sheets emerge during embryogenesis by a branching and growth of the epithelium. The surrounding mesenchyme is crucial for this process. We report that branching morphogenesis and the formation of a new epithelium from the mesenchyme in the embryonic kidney can be blocked by a monoclonal antibody reacting with a surface glycolipid, disialoganglioside G D3 . In contrast, a more than 10-fold excess of antibodies to adhesive glycoproteins (N-CAM, L -CAM, fibronectin) fails to inhibit morphogenesis. Although the anti-G D3 antibody affected epithelial development, the disialoganglioside G D3 was expressed not in the epithelium, but in the mesenchyme surrounding the develo…

medicine.drug_classMesenchymeMorphogenesisFluorescent Antibody TechniqueBiologyKidneyMonoclonal antibodyEpitheliumGeneral Biochemistry Genetics and Molecular BiologyMesodermMiceOrgan Culture TechniquesCell–cell interactionGangliosidesMorphogenesismedicineAnimalsGanglioside GD3Embryonic InductionMembrane GlycoproteinsAntibodies MonoclonalEmbryonic stem cellEpitheliumFibronectinsCell biologyFibronectinmedicine.anatomical_structureBiochemistryAntigens Surfacebiology.proteinUreterCell Adhesion MoleculesCell
researchProduct

Multiple Resistance to Betalactam Antibiotics, Azithromycin or Moxifloxacin in Implant Associated Bacteria

2013

Background Antibiotics are more and more frequently prescribed in dentistry for prevention and treatment of oral diseases. Bacterial resistance to these agents is clearly increasing, including even previously susceptible micro-organisms and true pathogens. The aim of the present investigation was to examine resistant bacterial strains with respect to possible multiple antibiotic resistance. Methods In a previous investigation, implant-associated bacteria were tested first as mixed cultures and again as pure isolates (n = 138) for resistance to one of five antibiotics (ampicillin/AM, ampicillin + sulbactam/AB, azithromycin/AZ, penicillin/PG, moxifloxacin/MX) using the Etest. The resistance o…

medicine.drug_classMoxifloxacinAntibioticsMicrobial Sensitivity TestsDrug resistanceAzithromycinbeta-LactamsGeneral Biochemistry Genetics and Molecular BiologyMicrobiologyAntibiotic resistanceMoxifloxacinAmpicillinmedicineHumansEtestDental ImplantsAza CompoundsBacteriabusiness.industryDrug Resistance MicrobialSulbactamDrug Resistance MultiplePenicillinQuinolinesbusinessFluoroquinolonesmedicine.drugClinical Laboratory
researchProduct

Immunonegative Staining: Epitope Localization on Macromolecules

1996

Relevant literature relating to immunonegative staining is reviewed and integrated with current research of the author and others. The immunonegative staining procedure has been utilized for the study of epitope localization on immune complexes formed from keyhole limpet hemocyanin type 2 (KLH2) di- and multidecamers, and the 20S and 26S proteasome from Xenopus laevis. The IgG linkage pattern of molecules in small immune complexes is considered to provide the most reliable indication of epitope location. For both KLH2 and the 20S proteasome, using domain-specific monoclonal antibodies and a 32-kDa (p32) subunit-specific polyclonal antibody, respectively, it is shown that epitopes (KLH2, sub…

medicine.drug_classProtein subunitXenopusBiologybiology.organism_classificationMonoclonal antibodyMolecular biologyGeneral Biochemistry Genetics and Molecular BiologyEpitopeProteasomePolyclonal antibodiesmedicinebiology.proteinBiophysicsMolecular BiologyKeyhole limpet hemocyaninMacromoleculeMethods
researchProduct